Hotel Monasterio
Cusco
Originally built as a monastery (hence the name) in 1592, this structure has been lovingly restored and transformed into one of Peru's finest destination properties, full of historical charm. All of the 125 rooms have striking original touches, and the property uses warm reds, yellows, and greens to complement the existing stone. Common areas have beautiful Spanish art and art tours will introduce guests to the work. Guests can literally breathe easier at Monasterio, since the hotel will pipe in oxygen (for an additional cost) for those struggling with altitude issues. An excellent restaurant and bar are two more reasons that Monasterio is a top property in Cusco.

Las Casitas del Colca
Colca Valley
Nestled deep in the heart of southwestern Peru is the exquisite Las Casitas del Colca, a perfect getaway for those looking to step off the beaten path and enjoy some pampering. Guests occupy their own charming cottage, complete with four-poster bed, heated stone floors, fireplace, enormous bathroom with outdoor shower – even a private plunge pool from which to enjoy the magnificent views. Choose from a menu of daily activities that include horseback riding, cooking classes, bicycle rides and, of course, an opportunity to see the famous condors at Colca Canyon. Meals are tasty affairs that feature fresh vegetables from the property’s own organic garden and local wines. A stay at Colca Canyon is highly recommended for honeymooners and adventurous travelers who relish some time to relax and explore a little-known but extremely rewarding area of Peru.

Sanctuary Lodge
Machu Picchu
The only property adjacent to the ancient citadel of Machu Picchu, Sanctuary Lodge offers access to the ruins that other hotels simply do not have, so you can check out the peaceful sunrise and starry nights away from other tourists. All guestrooms have dramatic views of the mountains and jungle across the Urubamba River and most rooms feature a living room area with spacious wooden terraces. Morning is a popular time to wander around the garden area and enjoy a champagne breakfast with stunning views of Machu Picchu. Meals are on a full board basis, served in the lodge's two restaurants, which cook up a tasty array of international and Peruvian cuisine.

Inkaterra Machu Picchu Pueblo Hotel
Machu Picchu / Aguas Calientes
This charming resort is set amid a nature preserve and is built to resemble a traditional Andean village. Accommodation consists of one- and two-story whitewashed cottages constructed using local materials; a stone pathway links the entire resort. Inside the cottages are a working fireplace, outdoor shower, entertainment center, and a sitting area complete with complimentary Pisco. The property surrounding the resort boasts the largest publicly viewable collection of orchids in the world and guests may enjoy walks with the on-site naturalist guide to learn about the orchids, birds, and wildlife. After a day exploring, guests relax in the hotel's den and bar to enjoy the late afternoon tea and refreshments prepared daily before dinner.

Miraflores Park Hotel
Lima
With the best location in town (the leafy neighborhood of Miraflores), this beautiful boutique hotel overlooks the Pacific Ocean and has 82 guest rooms. The opulent rooms feature large windows with spectacular ocean views and spacious black marble bathrooms, complete with their own private saunas. Guests can take their meals on the rooftop and then relax by the refreshing swimming pool -- designed with a cool infinity effect and wonderful view over the ocean -- or indulge in a relaxing treatment at the Zest Spa, which offers a wide array of treatments that incorporate indigenous products from Peru and the Amazon.

Sol y Luna
Urubamba / Sacred Valley
This beautiful little property is surrounded by the Andes Mountains and offers magnificent views - in fact, you may be tempted to skip any scheduled touring and spend the day in a recliner, watching the clouds drift over the mountain tops and taking advantage of the pool, tennis courts, and horse-back riding. The 28 round yellow bungalows are simple but have stylish, modern bathrooms and outdoor decks, and the property has plenty of flowers everywhere. Lower than Cusco (so altitude is not an issue) and closer to Machu Picchu, this is a perfect spot to tour the market at Pisac and the ruins of Ollantaytambo before traveling by train to Machu Picchu.

Inkaterra La Casona
Cusco
One of the first buildings constructed over the site of the original Inca complex of Cusco, this former colonial manor house is now one of the finest boutique hotels in town. The elegance and charm of its past is preserved but the property has been refurbished complete with i-pod stations and controlled heated flooring. Unwind in one of the 11 suites, each of which feature Spanish antiques, sunken bathtubs, wood-burning fireplaces and outdoor verandahs showcasing the sweeping views of the Andes. Complete your stay with a visit to the spa or check out Cusco's culturally vibrant central square, just a few steps away.

Aqua Expeditions
Amazon River
Visitors to the Amazon have never had a truly luxurious way to explore its waterways – until now. The M/V Aqua can accommodate up to 24 cruise passengers in 12 ultra-spacious air-conditioned suites with large picture windows that showcase the ever-changing panorama. The top-level observation deck provides an excellent perch from which to watch the river slide by and enjoy a little down time. Guests can choose to stay on board for 3, 4 or 7 nights; each day, naturalist guides lead passengers on excursions aboard comfortable motorized skiffs that enable exploration deep into the tributaries of the rainforest. In the evening, lectures introduce the rich diversity of flora and fauna that make their homes in the rainforest, and then guests feast on gourmet Peruvian cuisine and South American wine.